Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation

14 Jan 2020

Abstract excerpt

Lower respiratory infections, such as community-acquired pneumonia (CAP), and chronic obstructive pulmonary disease (COPD) rank among the most frequent causes of death worldwide. Improved diagnostics and profound pathophysiological insights are urgent clinical needs. In our cohort, we analysed transcriptional networks of peripheral blood mononuclear cells (PBMCs) to identify central regulators and potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31937830
DOI: 10.1038/s41598-019-57108-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbationPMID 31937830Read ↗

Comparative transcriptomic analyses of peripheral blood mononuclear cells of patients with non-pneumonia and severe pneumonia at 1 year-Long-COVID-19Semantic proximity Read ↗

Gene Expression Profiles Reveal Distinct Mechanisms Driving Chronic Obstructive Pulmonary Disease ExacerbationsSemantic proximity Read ↗

Identification of Potential Key Long Non-Coding RNAs and Target Genes Associated with Pneumonia Using Long Non-Coding RNA Sequencing (lncRNA-Seq): A Preliminary StudySemantic proximity Read ↗

Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary diseaseSemantic proximity Read ↗

Consensus transcriptional states describe human mononuclear phagocyte diversity in the lung across health and diseaseSemantic proximity Read ↗

A multicenter prospective study of comprehensive metagenomic and transcriptomic signatures for predicting outcomes of patients with severe community-acquired pneumoniaSemantic proximity Read ↗

Integrative Analysis Identifies MCEMP1 and VCAN as Novel Hpoxia-Associated Biomarkers in COPD through Multi-Omics and Machine Learning AproachesSemantic proximity Read ↗

Pathogen-specific host responses define distinct pneumonia endotypes in the human lungSemantic proximity Read ↗

A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumoniaSemantic proximity Read ↗

A single-cell transcriptomic landscape of the lungs of patients with COVID-19Semantic proximity Read ↗

Systematic analysis of transcriptomic profiles of COPD airway epithelium using next-generation sequencing and bioinformaticsSemantic proximity Read ↗

Prospective multicenter study identifying prognostic biomarkers and microbial profiles in severe CAP using BALF, blood mNGS, and PBMC transcriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.