Article
One single basic amino acid at the ω-1 or ω-2 site is a signal that retains glycosylphosphatidylinositol-anchored protein in the plasma membrane of Aspergillus fumigatus.
Eukaryotic cell - 1 Jun 2013
Ouyang Haomiao, Chen Xiaomin, Lü Yang, Wilson Iain B H, Tang Guomin, Wang Aoquan, Jin Cheng
Abstract excerpt
Although the plasma membrane is the terminal destination for glycosylphosphatidylinositol (GPI) proteins in higher eukaryotes, cell wall-attached GPI proteins (GPI-CWPs) are found in many fungal species. In yeast, some of the cis-requirements directing localization of GPI proteins to the plasma membrane or cell wall are now understood. However, it remains to be determined how Aspergillus fumigatus, an...
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