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Article

Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope.

Cell reports - 25 Apr 2013

Jokhi Vahbiz, Ashley James, Nunnari John, Noma Akiko, Ito Naoto, Wakabayashi-Ito Noriko, Moore Melissa J, Budnik Vivian

Abstract excerpt

A previously unrecognized mechanism through which large ribonucleoprotein (megaRNP) granules exit the nucleus is by budding through the nuclear envelope (NE). This mechanism is akin to the nuclear egress of herpes-type viruses and is essential for proper synapse development. However, the molecular machinery required to remodel the NE during this process is unknown. Here, we identify Torsin, an AAA-ATPase that in...

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Identifiers

PMID: 23583177
DOI: 10.1016/j.celrep.2013.03.015
PMCID: PMC3683601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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