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Article

TP53 p.R337H is a conditional cancer-predisposing mutation: further evidence from a homozygous patient.

BMC cancer - 9 Apr 2013

Giacomazzi Juliana, Selistre Simone, Duarte Juliana, Ribeiro Jorge Pinto, Vieira Paulo J C, de Souza Macedo Gabriel, Rossi Cristina, Czepielewski Mauro, Netto Cristina Brinkmann Oliveira, Hainaut Pierre, Ashton-Prolla Patricia

Abstract excerpt

BACKGROUND: Adrenocortical carcinomas (ACCs) are among the most common childhood cancers occurring in infants affected with the Li-Fraumeni and Li- Fraumeni-like (LFS/LFL) syndromes, which are caused by dominant germline mutations in the TP53 gene. In Brazil, a particular mutation, occurring in t...

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Identifiers

PMID: 23570263
DOI: 10.1186/1471-2407-13-187
PMCID: PMC3637265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23570263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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