Interplay of Vitamin D and CYP3A4 Polymorphisms in Endocrine Disorders and Cancer

Abstract excerpt

Vitamin D has received considerable optimistic attention as a potentially important factor in many pathological states over the past few decades. However, the proportion of the active form of vitamin D metabolites responsible for biological activity is highly questionable in disease states due to flexible alterations in the enzymes responsible for their metabolism. For instance, CYP3A4 plays a crucial role in the...

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