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Article

FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential

4 Apr 2013

Abstract excerpt

Melanoma is the most aggressive skin cancer; there is no cure in advanced stages. Identifying molecular participants in melanoma progression may provide useful diagnostic and therapeutic tools. FK506 binding protein 51 (FKBP51), an immunophilin with a relevant role in developmental stages, is highly expressed in melanoma and correlates with aggressiveness and therapy resistance. We hypothesized a role for FKBP51...

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PMID: 23559012
DOI: 10.1038/cddis.2013.109

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