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Article

The coagulase of Staphylococcus aureus 8325-4. Sequence analysis and virulence of site-specific coagulase-deficient mutants.

Molecular microbiology - 1 Mar 1990

Phonimdaeng P, O'Reilly M, Nowlan P, Bramley A J, Foster T J

Abstract excerpt

The sequence of the coagulase gene (coa) from Staphylococcus aureus strain 8325-4 is reported. The deduced amino acid sequence of the coagulase protein is compared with previously reported sequences of coagulases from strains 213 and BB. The secreted mature forms of coagulase proteins are composed of three distinct segments: (i) the N-terminal 150-270 residues, which are c. 50% identical, (ii) a central region...

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PMID: 2355852
DOI: 10.1111/j.1365-2958.1990.tb00606.x

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