Molecular analysis of the coagulase gene in clinical and nasal carrier isolates of methicillin-resistant Staphylococcus aureus by restriction fragment length polymorphism.

Abstract excerpt

OBJECTIVES: The coagulase enzyme, encoded by the coa gene, is an important virulence factor of Staphylococcus aureus and can be used for typing of S. aureus isolates. In this study, coa gene typing was used to study the epidemiology of S. aureus at a university hospital in Hamadān (Iran). METHODS: A total of 200 S. aureus strains were analysed, among which 150 were isolated from clinical samples and 50 were from...

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