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Article

JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1.

BMC cancer - 4 Apr 2013

Zhan Xia, Feng Xiaobing, Kong Ying, Chen Yi, Tan Wenfu

Abstract excerpt

BACKGROUND AND METHODS: In addition to possess cross drug resistance characteristic, emerging evidences have shown that multiple-drug resistance (MDR) cancer cells exhibit aberrant metastatic capacity when compared to parental cells. In this study, we explored the contribution of c-Jun N-terminal kinases (JNK) signaling to the mesenchymal phenotypes and the aberrant motile capacity of MDR cells utilizing a well...

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Identifiers

PMID: 23557251
DOI: 10.1186/1471-2407-13-180
PMCID: PMC3646674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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