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Article

Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer

30 Sept 2012

Abstract excerpt

Gastric cancer stem-like cells (GCSCs) have been identified to possess the ability of self-renewal and tumor initiation. However, the mechanisms involved remain largely unknown. Here, we isolated and characterized the GCSCs by side population (SP) sorting procedure and cultured sphere cells (SC) from human gastric cancer cell lines SGC-7901, BGC-823, MGC-803, HGC-27 and MKN-28. The sorting and culture assay...

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PMID: 23554769
DOI: 10.7555/jbr.26.20120045

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