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Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties

29 Nov 2012

Abstract excerpt

The cancer stem cell theory hypothesizes that cancer stem cells (CSCs), which possess self-renewal and other stem cell properties, are regarded as the cause of tumor formation, recurrence and metastasis. The isolation and identification of CSCs could help to develop novel therapeutic strategies specifically targeting CSCs. In this study, we enriched gastric cancer stem cells through spheroid body formation by...

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Identifiers

PMID: 23229446
DOI: 10.3892/ijo.2012.1720

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