Article
Phenotype and steroidogenic potential of PDGFRα-positive rat neonatal peritubular cells.
Molecular and cellular endocrinology - 15 Jun 2013
Landreh Luise, Stukenborg Jan-Bernd, Söder Olle, Svechnikov Konstantin
Abstract excerpt
Platelet-derived growth factor receptor α (PDGFRα)-positive peritubular cells (PTCs) are suggested to be putative stem Leydig cells. At present little is known about their phenotype and steroidogenic potential. We isolated highly purified PDGFRα-positive neonatal PTCs by magnetic cell sorting (MACS) from 8dpp rat testes and characterized them in vitro. We have demonstrated that PDGFRα-positive PTCs have a mixed...
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