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Article

microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy

28 Mar 2013

Abstract excerpt

STUDY QUESTION: Does vasectomy impact microRNA (miRNA) expression in the epididymis and seminal microvesicles (SMVs) in a non-reversible manner? SUMMARY ANSWER: The miRNA signature in the epididymis and SMVs is altered by vasectomy and only partially restored after vasovasostomy surgery. WHAT IS KNOWN ALREADY: Vasectomy modifies the epididymal transcriptome and triggers non-reversible changes that affect sperm...

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PMID: 23539611
DOI: 10.1093/humrep/det088

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