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Article

Gene expression signatures of coronary heart disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2013

Joehanes Roby, Ying Saixia, Huan Tianxiao, Johnson Andrew D, Raghavachari Nalini, Wang Richard, Liu Poching, Woodhouse Kimberly A, Sen Shurjo K, Tanriverdi Kahraman, Courchesne Paul, Freedman Jane E, O'Donnell Christopher J, Levy Daniel, Munson Peter J

Abstract excerpt

OBJECTIVE: To identify transcriptomic biomarkers of coronary heart disease (CHD) in 188 cases with CHD and 188 age- and sex-matched controls who were participants in the Framingham Heart Study. APPROACH AND RESULTS: A total of 35 genes were differentially expressed in cases with CHD versus controls at false discovery rate<0.5, including GZMB, TMEM56, and GUK1. Cluster analysis revealed 3 gene clusters associated...

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Identifiers

PMID: 23539218
DOI: 10.1161/ATVBAHA.112.301169
PMCID: PMC3684247

Genes

GUK1
GZMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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