Article
Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer.
Breast cancer research : BCR - 28 Mar 2013
Katchman Benjamin A, Ocal I Tolgay, Cunliffe Heather E, Chang Yu-Hui, Hostetter Galen, Watanabe Aprill, LoBello Janine, Lake Douglas F
Abstract excerpt
INTRODUCTION: Quiescin sulfhydryl oxidase 1 (QSOX1) oxidizes sulfhydryl groups to form disulfide bonds in proteins. Tumor specific expression of QSOX1 has been reported for numerous tumor types. In this study, we investigate QSOX1 as a marker of breast tumor progression and evaluate the role of Q...
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