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Article

Low level of sequence diversity at merozoite surface protein-1 locus of Plasmodium ovale curtisi and P. ovale wallikeri from Thai isolates.

PloS one - 1 Jan 2013

Putaporntip Chaturong, Hughes Austin L, Jongwutiwes Somchai

Abstract excerpt

BACKGROUND: The merozoite surface protein-1 (MSP-1) is a candidate target for the development of blood stage vaccines against malaria. Polymorphism in MSP-1 can be useful as a genetic marker for strain differentiation in malarial parasites. Although sequence diversity in the MSP-1 locus has been extensively analyzed in field isolates of Plasmodium falciparum and P. vivax, the extent of variation in its homologues...

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Identifiers

PMID: 23536840
DOI: 10.1371/journal.pone.0058962
PMCID: PMC3594193

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