Article
Phylogenetic considerations in designing a broadly protective multimeric L2 vaccine.
Journal of virology - 1 Jun 2013
Jagu Subhashini, Kwak Kihyuck, Schiller John T, Lowy Douglas R, Kleanthous Harold, Kalnin Kirill, Wang Chenguang, Wang Hsu-Kun, Chow Louise T, Huh Warner K, Jaganathan Kilvani S, Chivukula Sudha V, Roden Richard B S
Abstract excerpt
While the oncogenic human papillomavirus (HPV) types with the greatest medical impact are clustered within the α9 and α7 species, a significant fraction of cervical cancers are caused by α5, α6, and α11 viruses. Benign genital warts are caused principally by the α10 viruses HPV6 and HPV11. In an...
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