Article
Epstein-Barr virus negativity among individuals older than 60 years is associated with HLA-C and HLA-Bw4 variants and tonsillectomy.
Journal of virology - 1 Jun 2013
Durovic Bojana, Gasser Olivier, Gubser Patrick, Sigle Jörg, Hirsch Hans H, Stern Martin, Buser Andreas, Hess Christoph
Abstract excerpt
Epstein-Barr virus (EBV) infects ≈ 95% of the adult population. The factors that confer protection in the remaining ≈ 5% remain unknown. In an exploratory study, we assessed immunogenetic factors and tonsillectomy in a cohort of 17 EBV-negative and 39 EBV-positive healthy individuals aged >60 yea...
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