Article
An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.
Molecular endocrinology (Baltimore, Md.) - 1 May 2013
Pitetti Jean-Luc, Calvel Pierre, Zimmermann Céline, Conne Béatrice, Papaioannou Marilena D, Aubry Florence, Cederroth Christopher R, Urner Françoise, Fumel Betty, Crausaz Michel, Docquier Mylène, Herrera Pedro Luis, Pralong François, Germond Marc, Guillou Florian, Jégou Bernard, Nef Serge
Abstract excerpt
Testis size and sperm production are directly correlated to the total number of adult Sertoli cells (SCs). Although the establishment of an adequate number of SCs is crucial for future male fertility, the identification and characterization of the factors regulating SC survival, proliferation, an...
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