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Identification of follicle‐stimulating hormone‐responsive genes in Sertoli cells during early postnatal mouse testis development

20 May 2023

Abstract excerpt

Abstract Background In the mouse testis, Sertoli cells rapidly divide during a narrow window of time pre‐pubertally and differentiate thereafter. The number of Sertoli cells determines the testis size and germ cell‐carrying capacity. Follicle‐stimulating hormone (FSH) binds its cognate FSH‐receptors expressed on Sertoli cells and acts as a mitogen to regulate their proliferation. Fshb−/− mutant adult male mice...

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PMID: 37208854
DOI: 10.1111/andr.13459

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