Article
[Epidermal growth factor receptor mutations and radiotherapy in non-small cell lung cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Mar 2013
Zhong Xing, Wang Jin
Abstract excerpt
Radiotherapy plays a pivotal role in the treatment for lung cancer. Epidermal growth factor receptor (EGFR) mutation in non-small cell lung cancer (NSCLC) which predicts tyrosine kinase inhibitor (TKI) treatment response may also has effect on radiation response. NSCLC harboring kinase-domain mutations in EGFR exhibits enhanced radio-sensitivity due to dramatically diminished capacity to resolve radiation-induced...
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