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Article

Deletion of dpy-19 like 2 (DPY19L2) gene is associated with total but not partial globozoospermia.

Reproduction, fertility, and development - 1 May 2020

Alimohammadi Fatemeh, Ebrahimi Nasab Mahya, Rafaee Alemeh, Hashemi Mehrdad, Totonchi Mehdi, Mohseni Meybodi Anahita, Sadighi Gilani Mohammad Ali, Sabbaghian Marjan

Abstract excerpt

The dpy-19 like 2 (DPY19L2) gene is the most common genetic cause of globozoospermia characterised by the production of round-headed spermatozoa without an acrosome. The present study was performed on 63 men with globozoospermia and 41 normozoospermic individuals to evaluate the frequency of the DPY19L2 gene and exons; deletion and genetic changes in exons 1, 5, 7-11, 19, 21 and interval introns; and some...

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PMID: 32312381
DOI: 10.1071/RD19025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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