Article
Mouse urinary peptides provide a molecular basis for genotype discrimination by nasal sensory neurons.
Nature communications - 1 Jan 2013
Sturm Theo, Leinders-Zufall Trese, Maček Boris, Walzer Mathias, Jung Stephan, Pömmerl Beate, Stevanović Stefan, Zufall Frank, Overath Peter, Rammensee Hans-Georg
Abstract excerpt
Selected groups of peptides, including those that are presented by major histocompatibility complex (MHC) proteins, have been proposed to transmit information to the olfactory system of vertebrates via their ability to stimulate chemosensory neurons. However, the lack of knowledge about such peptides in natural sources accessible for nasal recognition has been a major barrier for this hypothesis. Here we analyse...
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