Article
Genomic variation in the vomeronasal receptor gene repertoires of inbred mice.
BMC genomics - 21 Aug 2012
Wynn Elizabeth H, Sánchez-Andrade Gabriela, Carss Keren J, Logan Darren W
Abstract excerpt
BACKGROUND: Vomeronasal receptors (VRs), expressed in sensory neurons of the vomeronasal organ, are thought to bind pheromones and mediate innate behaviours. The mouse reference genome has over 360 functional VRs arranged in highly homologous clusters, but the vast majority are of unknown function. Differences in these receptors within and between closely related species of mice are likely to underpin a range of...
Topics
- Animals
- Genetic Variation
- Genome
- High-Throughput Nucleotide Sequencing
- Mice
- Polymorphism, Single Nucleotide
- Receptors, Pheromone
- Vomeronasal Organ