Article
Transduction of Wnt11 promotes mesenchymal stem cell transdifferentiation into cardiac phenotypes.
Stem cells and development - 1 Oct 2011
He Zhisong, Li Hongxia, Zuo Shi, Pasha Zeeshan, Wang Yigang, Yang Yueting, Jiang Wenping, Ashraf Muhammad, Xu Meifeng
Abstract excerpt
Transplantation of mesenchymal stem cells (MSCs) has emerged as a potential treatment for ischemic heart repair. Previous studies have suggested that Wnt11 plays a critical role in cardiac specification and morphogenesis. In this study, we examined whether transduction of Wnt11 directly increases...
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