Article
Lipid A mutants of Vibrio cholerae: isolation and partial characterization.
Biochemical and biophysical research communications - 31 May 1990
Paul S, Sen A K, Banerjee N, Chatterjee A N, Das J
Abstract excerpt
Vibrio cholerae mutants resistant to common antibiotics and neutral and anionic detergents were isolated. Analysis of isolated outer membranes revealed a significant deficiency in the acylation of lipid A in the resistant strains. The content of amide-linked and ester-bound fatty acids in the lipid A of the mutant strains compared to that of the wild type was about 50-56% and 29-37% respectively. This defect was...
Topics
- Drug Resistance, Microbial
- Fatty Acids
- Lipid A
- Lipopolysaccharides
- Mutation
- Vibrio cholerae