Article
Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2013
Palomaki Glenn E, Melillo Stephanie, Marrone Michael, Douglas Michael P
Abstract excerpt
This evidence review addresses whether type 2 diabetes genomic risk panels improve health outcomes (e.g., reduce rates of developing type 2 diabetes) in low- or high-risk adults; two clinical scenarios promulgated by commercial companies offering such testing. Evidence for the analytic validity of available genomic profiles was inadequate. Clinical validity ranged from inadequate to convincing for 30 variants...
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