Article
Randomized, double-blind, placebo-controlled trial of vitamin D supplementation in Parkinson disease.
The American journal of clinical nutrition - 1 May 2013
Suzuki Masahiko, Yoshioka Masayuki, Hashimoto Masaya, Murakami Maiko, Noya Miki, Takahashi Daisuke, Urashima Mitsuyoshi
Abstract excerpt
BACKGROUND: In our previous study, higher serum 25-hydroxyvitamin D [25(OH)D] concentrations and the vitamin D receptor (VDR) FokI CC genotype were associated with milder Parkinson disease (PD). OBJECTIVE: We evaluated whether vitamin D3 supplementation inhibits the progression of PD on the basis of patient VDR subgroups. DESIGN: Patients with PD (n = 114) were randomly assigned to receive vitamin D3 supplements...
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