Article
MCP-1 in psoriatic patients: effect of biological therapy.
The Journal of dermatological treatment - 1 Feb 2014
Lembo Serena, Capasso Rosanna, Balato Anna, Cirillo Teresa, Flora Filomena, Zappia Vincenzo, Balato Nicola, Ingrosso Diego, Ayala Fabio
Abstract excerpt
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is a chemokine locally and systemically augmented in psoriasis. A single nucleotide polymorphism in MCP-1 promoter region -2518A→G is associated with higher gene expression. OBJECTIVE: The aim was to evaluate MCP-1 plasma level in psoriatic patients and to relate any association in plasmatic and cutaneous MCP-1 with clinical improvement due to biological...
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