Article
The KRAS mutation detection within the initial management of patients with metastatic colorectal cancer: a status report in France in 2011.
European journal of cancer (Oxford, England : 1990) - 1 Jun 2013
Lièvre A, Artru P, Guiu M, Laurent-Puig P, Merlin J L, Sabourin J C, Viguier J, Bastie A, Seronde A, Ducreux M
Abstract excerpt
BACKGROUND: The detection of KRAS mutations is mandatory to initiate an anti-epidermal growth factor receptor (EGFR) antibody in the treatment of metastatic colorectal carcinoma (mCRC). PATIENTS AND METHODS: This observational retrospective study was performed in 160 French centres during a 2-week period in 2011. Its main objective was to evaluate the rate of KRAS testing in patients with mCRC having initiated...
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