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Article

RAS mutation testing in patients with metastatic colorectal cancer in French clinical practice: A status report in 2014.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 May 2018

Lièvre Astrid, Merlin Jean-Louis, Sabourin Jean-Christophe, Artru Pascal, Tong Sabine, Libert Lucie, Audhuy François, Gicquel Corinne, Moureau-Zabotto Laurence, Ossendza Roch-Anicet, Laurent-Puig Pierre, Ducreux Michel

Abstract excerpt

BACKGROUND: RAS (NRAS + KRAS) mutation testing is required in addition to simple KRAS testing prior to initiating anti-epidermal-growth-factor-receptor (EGFR) antibodies (MAb) as in metastatic colorectal cancer (mCRC). AIMS: To assess prescription and implementation rates of RAS/KRAS mutation testing. To describe the RAS/KRAS mutation test procedure and its impact on therapeutic strategy. PATIENTS AND METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29396127
DOI: 10.1016/j.dld.2017.12.029

Genes

KRAS
EGFR
NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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