Article
Transmission patterns of HIV-subtypes A/AE versus B: inferring risk-behavior trends and treatment-efficacy limitations from viral genotypic data obtained prior to and during antiretroviral therapy.
PloS one - 1 Jan 2013
Avidor Boaz, Turner Dan, Mor Zohar, Chalom Shirley, Riesenberg Klaris, Shahar Eduardo, Pollack Shimon, Elbirt Daniel, Sthoeger Zev, Maayan Shlomo, Olshtain-Pops Karen, Averbuch Diana, Chowers Michal, Istomin Valery, Anis Emilia, Mendelson Ella, Ram Daniela, Levy Itzchak, Grossman Zehava
Abstract excerpt
BACKGROUND: HIV subtypes A and CRF01_AE (A/AE) became prevalent in Israel, first through immigration of infected people, mostly intravenous-drug users (IVDU), from Former Soviet-Union (FSU) countries and then also by local spreading. We retrospectively studied virus-transmission patterns of these subtypes in comparison to the longer-established subtype B, evaluating in particular risk-group related differences....
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