Article
Pseudo-constitutivity of nitrate-responsive genes in nitrate reductase mutants.
Fungal genetics and biology : FG & B - 1 May 2013
Schinko Thorsten, Gallmetzer Andreas, Amillis Sotiris, Strauss Joseph
Abstract excerpt
In fungi, transcriptional activation of genes involved in NO3(-) assimilation requires the presence of an inducer (nitrate or nitrite) and low intracellular concentrations of the pathway products ammonium or glutamine. In Aspergillus nidulans, the two transcription factors NirA and AreA act synergistically to mediate nitrate/nitrite induction and nitrogen metabolite derepression, respectively. In all studied...
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