Article
Heterologous expression and regulation of the Neurospora crassa nit-4 pathway-specific regulatory gene for nitrate assimilation in Aspergillus nidulans.
Gene - 1 Apr 1991
Hawker K L, Montague P, Marzluf G A, Kinghorn J R
Abstract excerpt
The nirA gene of Aspergillus nidulans and the nit-4 gene of Neurospora crassa appear to be equivalent pathway-specific regulatory genes which mediate nitrate induction of nitrate reductase and nitrite reductase (NR and NiR) activities. We have transformed the nit-4 wild-type (wt) gene into the A. nidulans loss-of-function (pleiotropic negative) nirA 1 mutant strain. The nit-4 gene was found to complement the nirA...
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