Article
Genetic Variability of Bovine Viral Diarrhea Virus and Evidence for a Possible Genetic Bottleneck during Vertical Transmission in Persistently Infected Cattle.
PloS one - 1 Jan 2015
Dow Natalie, Chernick Adam, Orsel Karin, van Marle Guido, van der Meer Frank
Abstract excerpt
Bovine viral diarrhea virus (BVDV), a Pestivirus in the family Flaviviridae, is an economically important pathogen of cattle worldwide. The primary propagators of the virus are immunotolerant persistently infected (PI) cattle, which shed large quantities of virus throughout life. Despite the absence of an acquired immunity against BVDV in these PI cattle there are strong indications of viral variability that are...
Topics
- Animals
- Bovine Virus Diarrhea-Mucosal Disease
- Cattle
- Diarrhea Virus 1, Bovine Viral
- Genetic Variation
- Infectious Disease Transmission, Vertical
- Phylogeny