Article
Decreased expression of the satiety signal receptor CCKAR is responsible for increased growth and body weight during the domestication of chickens.
American journal of physiology. Endocrinology and metabolism - 1 May 2013
Dunn Ian C, Meddle Simone L, Wilson Peter W, Wardle Chloe A, Law Andy S, Bishop Valerie R, Hindar Camilla, Robertson Graeme W, Burt Dave W, Ellison Stephanie J H, Morrice David M, Hocking Paul M
Abstract excerpt
Animal domestication has resulted in changes in growth and size. It has been suggested that this may have involved selection for differences in appetite. Divergent growth between chickens selected for egg laying or meat production is one such example. The neurons expressing AGRP and POMC in the basal hypothalamus are important components of appetite regulation, as are the satiety feedback pathways that carry...
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