Article
Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight.
Physiological genomics - 1 May 2013
Ka Sojeong, Markljung Ellen, Ring Henrik, Albert Frank W, Harun-Or-Rashid Mohammad, Wahlberg Per, Garcia-Roves Pablo M, Zierath Juleen R, Denbow D Michael, Pääbo Svante, Siegel Paul B, Andersson Leif, Hallböök Finn
Abstract excerpt
Carnitine palmitoyl-CoA transferase-1B is a mitochondrial enzyme in the fatty acid oxidation pathway. In a previous study, CPT1B was identified as differentially expressed in the hypothalamus of two lines of chickens established by long-term selection for high (HWS) or low (LWS) body weight. Mammals have three paralogs (CPT1a, b and c) while nonmammalian vertebrates only have two (CPT1A, B). CPT1A is expressed in...
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