Article
The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age.
Arthritis research & therapy - 26 Feb 2013
Caorsi Roberta, Lepore Loredana, Zulian Francesco, Alessio Maria, Stabile Achille, Insalaco Antonella, Finetti Martina, Battagliese Antonella, Martini Giorgia, Bibalo Chiara, Martini Alberto, Gattorno Marco
Abstract excerpt
INTRODUCTION: Interleukin-1 (IL-1) blockade is the treatment of choice of cryopyrin associated periodic syndromes (CAPS). Anti-IL-1 monoclonal antibody (canakinumab) was recently registered. However no clear data are available on the optimal schedule of administration of this drug. The aim of the present study was to analyse the impact of canakinumab on CAPS patients in daily clinical practice and to identify the...
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