Article
Canakinumab for the treatment of cryopyrin-associated periodic syndromes.
Drugs of today (Barcelona, Spain : 1998) - 1 Oct 2009
Walsh Garry M
Abstract excerpt
Familial cold-induced autoinflammatory syndrome, Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease make up cryopyrin-associated periodic syndromes (CAPS). These are autoinflammatory inherited disorders caused by autosomal dominant gain-of-function mutations in the NLRP3 ge...
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