Article
Reconstructing past changes in locus-specific recombination rates.
BMC genetics - 25 Feb 2013
Cox Murray P, Holland Barbara R, Wilkins Matthew C, Schmid Jan
Abstract excerpt
BACKGROUND: Recombination rates vary at the level of the species, population and individual. Now recognized as a transient feature of the genome, recombination rates at a given locus can change markedly over time. Existing inferential methods, predominantly based on linkage disequilibrium patterns, return a long-term average estimate of past recombination rates. Such estimates can be misleading, but no analytical...
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