Article
Staphylococcus aureus SasA is responsible for binding to the salivary agglutinin gp340, derived from human saliva.
Infection and immunity - 1 Jun 2013
Kukita Kenji, Kawada-Matsuo Miki, Oho Takahiko, Nagatomo Mami, Oogai Yuichi, Hashimoto Masahito, Suda Yasuo, Tanaka Takuo, Komatsuzawa Hitoshi
Abstract excerpt
Staphylococcus aureus is a major human pathogen that can colonize the nasal cavity, skin, intestine, and oral cavity as a commensal bacterium. gp340, also known as DMBT1 (deleted in malignant brain tumors 1), is associated with epithelial differentiation and innate immunity. In the oral cavity, gp340 induces salivary aggregation with several oral bacteria and promotes bacterial adhesion to tissues such as the...
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