Article
Functions of cell surface-anchored antigen I/II family and Hsa polypeptides in interactions of Streptococcus gordonii with host receptors.
Infection and immunity - 1 Oct 2005
Jakubovics Nicholas S, Kerrigan Steven W, Nobbs Angela H, Strömberg Nicklas, van Dolleweerd Craig J, Cox Dermot M, Kelly Charles G, Jenkinson Howard F
Abstract excerpt
Streptococcus gordonii colonizes multiple sites within the human oral cavity. This colonization depends upon the initial interactions of streptococcal adhesins with host receptors. The adhesins that bind salivary agglutinin glycoprotein (gp340) and human cell surface receptors include the antigen I/II (AgI/II) family polypeptides SspA and SspB and a sialic acid-binding surface protein designated Hsa or GspB. In...
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