Article
Group A streptococcus adheres to pharyngeal epithelial cells with salivary proline-rich proteins via GrpE chaperone protein.
The Journal of biological chemistry - 22 Jun 2012
Murakami Jumpei, Terao Yutaka, Morisaki Ichijiro, Hamada Shigeyuki, Kawabata Shigetada
Abstract excerpt
Group A Streptococcus pyogenes (GAS) is an important human pathogen that frequently causes pharyngitis. GAS organisms can adhere to and invade pharyngeal epithelial cells, which are overlaid by salivary components. However, the role of salivary components in GAS adhesion to pharyngeal cells has not been reported precisely. We collected human saliva and purified various salivary components, including proline-rich...
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