Article
SNPs identified as modulators of ECG traits in the general population do not markedly affect ECG traits during acute myocardial infarction nor ventricular fibrillation risk in this condition.
PloS one - 1 Jan 2013
Pazoki Raha, de Jong Jonas S S G, Marsman Roos F, Bruinsma Nienke, Dekker Lukas R C, Wilde Arthur A M, Bezzina Connie R, Tanck Michael W T
Abstract excerpt
BACKGROUND: Ventricular fibrillation (VF) in the setting of acute ST elevation myocardial infarction (STEMI) is a leading cause of mortality. Although the risk of VF has a genetic component, the underlying genetic factors are largely unknown. Since heart rate and ECG intervals of conduction and repolarization during acute STEMI differ between patients who do and patients who do not develop VF, we investigated...
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