Article
A single-nucleotide polymorphism of miR-196a-2 and vitiligo: an association study and functional analysis in a Han Chinese population.
Pigment cell & melanoma research - 1 May 2013
Huang Ye, Yi Xiuli, Jian Zhe, Wei Chao, Li Shuli, Cai Chuan, Zhang Ping, Li Kai, Guo Sen, Liu Ling, Shi Qiong, Gao Tianwen, Li Chunying
Abstract excerpt
Recent evidence indicates that oxidative stress and genetic factors play an important role in the pathogenesis of vitiligo. SNPs in miRNAs involved in oxidative stress could potentially influence the development of vitiligo. In this case-control study, we investigated the association of a functional SNP of rs11614913 in miR-196a-2 with risk of vitiligo. A significantly lower risk of vitiligo was associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
