Article
Overexpression of TTRAP inhibits cell growth and induces apoptosis in osteosarcoma cells.
BMB reports - 1 Feb 2013
Zhou Caihong, Shen Qi, Xue Jinglun, Ji Chaoneng, Chen Jinzhong
Abstract excerpt
TTRAP is a multi-functional protein that is involved in multiple aspects of cellular functions including cell proliferation, apoptosis and the repair of DNA damage. Here, we demonstrated that the lentivirus-mediated overexpression of TTRAP significantly inhibited cell growth and induced apoptosis in osteosarcoma cells. The ectopic TTRAP suppressed the growth and colony formation capacity of two osteosarcoma cell...
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