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Article

Visual signal pathway reorganization in the Cacna1f mutant rat model.

Investigative ophthalmology & visual science - 19 Mar 2013

Tao Ye, Chen Tao, Liu Bei, Xue Jun Hui, Zhang Lei, Xia Feng, Pang Ji-Jing, Zhang Zuo Ming

Abstract excerpt

PURPOSE: To elucidate the underlying pathologic mechanism of congenital stationary night blindness (CSNB) by examining the characteristics of electrical signal transmission within the inner retinal circuit after Cacna1f gene mutation. METHODS: Retinas isolated from the spontaneous Cacna1f mutant rats or wild-type rats were placed into a recording chamber, with the ganglion cell layer facing the biochip electrode...

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Identifiers

PMID: 23425697
DOI: 10.1167/iovs.12-10706

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