Article
Retrospective analysis of whole genome sequencing compared to prospective typing data in further informing the epidemiological investigation of an outbreak of Shigella sonnei in the UK.
Epidemiology and infection - 1 Dec 2013
McDonnell J, Dallman T, Atkin S, Turbitt D A, Connor T R, Grant K A, Thomson N R, Jenkins C
Abstract excerpt
The aim of this study was to retrospectively assess the value of whole genome sequencing (WGS) compared to conventional typing methods in the investigation and control of an outbreak of Shigella sonnei in the Orthodox Jewish (OJ) community in the UK. The genome sequence analysis showed that the strains implicated in the outbreak formed three phylogenetically distinct clusters. One cluster represented cases...
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