Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparative study on the metabolic activation of 3,4-benzo[a]pyrene to mutagens by aorta smooth muscle cells of rat and rabbit.

Mutation research - 1 May 1990

Zwijsen R M, van Kleef E M, Alink G M

Abstract excerpt

The mutagenic activation of benzo[a]pyrene (BaP) after exposure to aorta smooth muscle cells of different origin was examined. Three test systems with different genetic endpoints--sister-chromatid exchange (SCE), gene mutation at the hypoxanthine guanine phosphoribosyl transferase (HGPRT) locus and unscheduled DNA synthesis (UDS)--were used. Treatment of rat and rabbit aorta smooth muscle cells with BaP (1-6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Genes
Share to Hypoxanthine Phosphoribosyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenicity Tests

Share to Mutagens

Share to Mutation

Share to Rabbits

Source

Identifiers

PMID: 2342494
DOI: 10.1016/0027-5107(90)90048-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

A comparative study on the metabolic activation of 3,4-benzo[a]pyrene to mutagens by aorta smooth muscle cells of rat and rabbit.PMID 2342494Read ↗

International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/1. Mutational events in the etiology of arteriosclerotic plaques.Semantic proximity Read ↗

Chronic exposure to the carcinogenic compound benzo[a]pyrene induces larger and phenotypically different atherosclerotic plaques in ApoE-knockout mice.Semantic proximity Read ↗

Glutathione transferase activity in human vessels and in cultured arterial smooth muscle cells.Semantic proximity Read ↗

The induction of proliferative vascular smooth muscle cell phenotypes by benzo[a]pyrene does not involve mutational activation of ras genes.Semantic proximity Read ↗

Environmental carcinogens and mutational pathways in atherosclerosis.Semantic proximity Read ↗

International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/2. Shared risk factors for cancer and atherosclerosis--a review of the epidemiological evidence.Semantic proximity Read ↗

International Commission for Protection Against Environmental Mutagens and Carcinogens. Report of ICPEMC Subcommittee 7/1. The possible involvement of somatic mutations in the development of atherosclerotic plaques.Semantic proximity Read ↗

DNA damage and repair in atherosclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.