Article
Impact of influenza virus escape-mutations on influenza detection by the rapid influenza diagnostic test.
Journal of medical virology - 1 Apr 2013
Yi Hwajung, Kim Young-Hoon, Kim Jun-Sub, Lee Nam-Joo, Shin Kyeongcheol, Choi Jang-Hoon, Kwon Donghyok, Lee Joo-Yeon, Kang Chun
Abstract excerpt
During the influenza pandemic of 2009-2010, rapid influenza diagnostic tests (RIDTs) were used to detect influenza viral infections because they are quick and simple to use. However, retrospective studies showed that RIDTs performed poorly when used to diagnose pandemic viral infections. Determining how amino acid sequence changes in pandemic or epidemic influenza viral antigens impact clinical value of RIDTs has...
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